蛋白质的功能与结构预测汇编.pptVIP

基础生物信息学及应用;第Ⅲ部分生物分子信息的分析;本章内容： 蛋白质家族和结构域数据库 蛋白质功能预测 蛋白质结构预测;第一节 蛋白质家族和结构域数据库;1、蛋白质模体及结构域数据库;蛋白质模体及结构域数据库;A domain is also a conserved sequence pattern, defined as an independent functional and structural unit. Domains are normally longer than motifs. A domain consists of more than 40 residues and up to 700 residues, with an average length of 100 residues. A domain may or may not include motifs within its boundaries. Examples，transmembrane domains， ligand-binding domains.;Identification of motifs and domains heavily relies on multiple sequence alignment as well as profile and hidden Markov