11本N胆碱受体阻断药分析.ppt

胆碱受体阻断药（Ⅱ）　　　　－N胆碱受体阻断药; ;第一节 神 经 节 阻 断 药;【药理作用】;作用部位;【临床应用】;第二节 骨 骼 肌 松 弛 药;;Hazards of Deep/Light Anesthesia;一、除极化型肌松药;depolarize end-plate Phase I Block initially fasciculation (disorganized contractions) ;2.作用特点：;琥珀胆碱(succinylcholine, 司可林 scoline);【药理作用】;【体内过程】;【临床应用】;【不良反应】;二、非除极化型肌松药;2.作用特点：;Typical drugs：;(d-tubocurarine);Although first suggested in 1912 by L?wen in Germany, purified extract of curare箭毒was introduced to anesthesia in 1941 by H.R Griffith of McGill to allow insensitivity to pain with light anesthesia while blocking reflex muscle movement. Curare was used as a blow dart投射and arrow poison by indigenous forest peoples of South America to paralyse their prey.;【药理作用】;【临床应用】;【不良反应】;1.除极化肌松药与竞争性肌松药有何异??？