Supercritical fluid extraction 超临界流体提取.pptVIP

Supercritical fluid extraction (SFE) / Supercritical fluid chromatography (SFC);Supercritical Fluid (SCF);Comparison of the properties of gas, Supercritical fluid and liquid;Advantages of Supercritical Fluids;Disadvantages of Supercritical Fluids;a Data taken from Refs. 62 and 63. B The density at 400 atm (p,,,,) end T, = 1.03 was calculated from compressibility data.” C measurements were made under saturated conditions if no pressure is specified or were performed at 25°C if no temperature is specified.;Benefits of supercritical carbon dioxide;Benefits of supercritical carbon dioxide Ctd.;Phase diagrams for CO2 and H2O;Supercritical Fluid extraction (SFE) / chromatography (SFC) Components;Commercial instruments;Liquid CO2 Cylinder;Pumps;Types of extraction cell;Columns;Restrictors;linear restrictor;Backpressure regulator;Detectors;Characteristics of supercritical fluid extraction;Supercritical fluid extraction;Supercritical fluid extraction;Off-line SFE;Device for the preparation of modified supercritical fluid;Schematic diagram of on-line SFE-SFC system a) CO2 cylinder b) pump c) extraction vessel d) cryotrapheater e) injection port f) chromatography column g) column oven h) detector i) transfer lines.;Advantages of on-line SFE;Directly coupled SFE-SFC;SFE/SFC;Recovery solubility;Percentage extraction versus time of extraction;Modifiers for SFE/SFC;The role of Modifier on SFE;The parameters effect on solubility;Reduced solubility parameter;Calculation of the solubility parameters, δ2;Solubility in carbon dioxide at different temperature and pressures;Method development for SFE;SFC characteristics: Faster linear velocity than LC Greater separation efficiency per unit time than LC Greater solute solubility than GC Greater mobile phase selectivity than GC Advantages compared to LC or GC: Compared to GC: Can separate thermally unstable compounds Can separate compounds beyond the volatility range of GC Compared to LC: Reduced analysis time;Comparison of MW