BEHAVIORALDISORDERSINCHILDHOOD重点.ppt

神经心理行为异常;精神发育迟滞 MENTAL RETARDATION, MR;精神发育迟滞MENTAL RETARDATION, MR;定 义 Definition 儿童在发育期间，智能显著低于同龄儿平均水平，导致或同时伴适应行为(adaptive behavior)缺陷;流行病 Epidemiology MR患病率: WHO (1997) 重度 4.0‰ 轻度 30.0‰; 病 因 Etiology;染色体畸变 Chromosomal Abnormalities;脆性X染色体综合征 Fragile X syndrome;先天性睾丸发育不全综合症 Klinefelter syndrome;先天性卵巢发育不全综合症Turner syndrome (45,X); 单基因遗传病　 Single Gene Abnormalities ;Figure 10. (click image to zoom) This blonde haired infant has the metabolic disorder, phenylketonuria (PKU);粘多糖病 (mucopolysaccharidos