FUTURA-长城会重点.ppt

* 磺达肝癸钠通过AT间接起到抑制Xa因子，进而起到抗凝作用。 合成的简单的分子结构和药理学原理决定了一定剂量范围的磺达肝癸钠在有效抗凝的同时，不过度干扰生理止血的作用。 * * * OASIS 5 was a randomized, double-blind, double-dummy trial in 20,078 patients with UA/NSTEMI in 576 centers in 41 countries Patients were eligible if they presented to hospital with symptoms of UA or MI without persistent ST elevation and at least two of the following additional criteria: age 60 years, troponin T or I or CK-MB above the upper limit of normal or ECG changes compatible with ischemia (i.e., ST depression at least 1 mm in two contiguous leads or T-wave inversion 3 mm or any dynamic ST shif