植物皮肤脱色剂的进展学案.ppt

中药研究 Traditional Chinese medicine researches 筛选: 300种醇和水提取物 Screening: alcohol and water soluble extracts of 300 kinds 单体---体外细胞试验 Monomer---in vitro cell culture tests 18ɑ-甘草酸双胺盐、芦荟素、苦参碱、肉桂酸、淫羊藿苷、红景天甙、橙皮苷、表没食子儿茶素没食子酸酯 18ɑ-Diammonium glycyrrbizinate, Aloin, Matrine, Cinnamic acid, Icariin,Ica, Salidroside, Hesperidin, EGCG 豚鼠试验 Guinea pig tests 橙皮苷、甘草素、甘草酸双胺盐 Hesperidin, Glycyrrhizin(Liquiritigenin), 18ɑ-Diammonium glycyrrbizinate 人体试验 Human study 存在问题 Existing problems 1. 植物单体提纯 Single plant extract purification 2. 化学特性 Chemical characteristics 3. 载体、基质 Vehicle an