Section B - Protein structure.pptVIP

Section B - Protein Structure Contents B1 Amino acids Structure, Charged side chains, Polar uncharged side chains, Nonpolar aliphatic side chains, Aromatic side chains B2 Protein structure and function Size and shapes, Primary structure, Secondary structure, Tertiary structure, Quaternary structure, Prosthetic groups, What do proteins do, Domains, motifs, Families and evolution B3 Protein analysis Protein Purification, Protein sequencing, Mass determination, X-ray crystallography and NMR, Functional analysis, Proteomics B1 Amino acids—Structure B1 Amino acids—Charged side chains B1 Amino acids— Polar uncharged side chains Ser Thr Asp Gln Cys B1 Amino acids— Nonpolar aliphatic side chains Gly Ala Val Leu Ile Met Pro B1 Amino acids— Aromatic side chains Phe Tyr Trp B2 Protein structure and function— Size and shapes B2 Protein structure and function— Primary structure A peptide bond is a chemical bond formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule, thereby releasing a molecule of water (H2O). B2 Protein structure and function— Secondary structure B2 Protein structure and function— Tertiary structure The different sections of a-helix, b-sheet, other minor secondary structure and connecting loops of a polypeptide fold in three dimensions B2 Protein structure and function— Quaternary structure B2 Protein structure and function— Prosthetic groups Coenzymes vitamins: NAD+ (B3) · NADP+ (B3) · Coenzyme A (B5) · THF / H4F (B9), DHF, MTHF · Ascorbic acid