膀胱肿瘤汽化电切术联合吡柔比星膀胱灌注化疗在浅表性膀胱癌患者中的应用效果.docVIP

膀胱肿瘤汽化电切术联合吡柔比星膀胱灌注化疗在浅表性膀胱癌患者中的应用效果 　　【摘要】 目的：分析汽化电切术联合吡柔比星膀胱灌注化疗在治疗浅表性膀胱癌中的临床疗效。方法：选取本院2010年6月-2012年6月收治的72例膀胱癌患者，按照随机数字表法，将患者分为试验组与对照组，每组各36例患者。其中，试验组采取汽化电切术联合吡柔比星膀胱灌注化疗，对照组仅行汽化电切术治疗，观察两组患者短期疗效并进行随访1年。结果：试验组患者术后留置导尿管时间（3.7±0.5）d，对照组患者术后留置导尿管时间（6.3±0.7）d，两组比较差异有统计学意义（P0.05）；试验组术后1年内出现肿瘤复发患者6例，对照组复发12例，两组患者肿瘤复发率比较差异具有统计学意义（P0.05）；随访1年试验组患者对治疗满意率为58.3%，高于对照组36.1%，两组比较差异有统计学意义（P0.05）。结论：汽化电切术联合吡柔比星膀胱灌注化疗对于浅表性膀胱癌的治疗效果较好，明显降低患者短期复发率，提高了患者对治疗满意度，值得在临床应用。 　　【关键词】 汽化电切术； 吡柔比星； 浅表性膀胱癌； 临床疗效 　　The Effect of Transurethral Resection Combined with Bladder Instillation of Pirarubicin Chemotherapy in Patients with Superficial Bladder Carcinoma/YANG Tian，FAN Zhi-qiang，WEN Shi-he.//Medical Innovation of China，2015，12（10）：024-026 　　【Abstract】 Objective：To analyze the clinical curative of transurethral resection combined with pirarubicin intravesical chemotherapy in the treatment of superficial bladder cancer.Method：72 cases patients from June 2010 to June 2012 were selected and analyzed.With the random number table， the patients were divided into experimental group and control group，36 cases in each group.The experimental group was treated the transurethral resection combined with pirarubicin intravesical chemotherapy，the control group was treated with transurethral resection.The short-term efficacy of two groups were observed and followed up for 1 year.Result：The catheter indwelling time of experimental group patients were（3.7±0.5） d，which in control group patients were（6.3±0.7）d，the difference was statistically significant（P0.05）；after operation one year， the experiment group 6 patients occurred tumor recurrence，12 cases of control group relapsed，compared two groups of patients tumor recurrence rate ，the difference has statistically significant（P0.05）.Conclusion：Electrovaporization combined with bladder instillation in treatment of superficial bladder cancer is better in effect.The patients’ short-term recurrence rate are significantly lower， and the patients’treatment satisf