TCellDevelopment-UniversityofVermont.pptVIP

Principles of ImmunologyB Cell Development3/16/06 “Hard work has a future payoff but laziness pays off now.” Anonymous Word/Terms List Class switching Clonal deletion Na?ve B cells Stromal cells TD antigens TI antigens B Cell Development Maturation-Stem cells to mature, na?ve B cells Activation-Ag binding; initiation of cell changes Differentiation-Cell division and changes into effector B cells (plasma cells) and memory B cells Lymphopoiesis Occurs in yolk sac, fetal liver then bone marrow throughout rest of life Mature, na?ve B cells released into circulation B cell produc