周环反应(北大教材).pptVIP

周环反应 一、周环反应的特点及其解析周环反应的理论 1. 特点 发生在Π体系中,通过环状过渡态进行,无中间体生成,新键的生成和旧键的破裂同时进行，反应具有立体选择性。 2.解析周环反应的理论： 1）分子轨道对称性守恒理论 （Woodward-Hoffmann Rules ） If the symmetries of both reactant and product orbitals match, the reaction is said to be symmetry allowed under the Woodward-Hoffmann Rules (these relate the electronic configuration of reactants to the type of pericyclic reaction and its stereochemical imperatives) If the symmetries of reactant and product orbitals do not correlate, the reaction is symmetry-disallowed and there no low energy concerted paths 2） 前线轨道理论(福井谦一） Fukui’s approach: