Receptor-MediatedEndocytosisexperiment.pptVIP

Receptor-Mediated Endocytosis experimental pathway 1.The process of receptor binding and internalization 2.The LDL receptor 3.Internalization signals Technique — electron microscope  Michael Brown Joseph Goldstein (University of Texas Medical School in Dallas) Richard Anderson Experimental pathway 1.The group incubated fibroblasts（成纤维细胞） from normal and FH subjects with LDL that had been covalently linked（共价结合） to the iron-containing protein ferritin（铁蛋白） .这个研究小组从正常的和带有LDL的FH中慢慢提取成纤维细胞，LDL被共价的连接于铁蛋白中。 3.A temperature of 4℃ Ligands（配体） can bind to the cell surface bu