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Calcineurinregulatesendothelialbarrierfunctionby.ppt

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Calcineurinregulatesendothelialbarrierfunctionby.ppt

Calcineurin regulates endothelial barrier function by interaction with and dephosphorylation of myosin phosphatase by Bernadett Kolozsvári, éva Bakó, Bálint Bécsi, Andrea Kiss, ágnes Czikora, Attila Tóth, Gy?rgy Vámosi, Pál Gergely, and Ferenc Erd?di Cardiovasc Res Volume 96(3):494-503 December 1, 2012 Published on behalf of the European Society of Cardiology. All rights reserved. ? The Author 2012. For permissions please email: journals.permissions@. CN is involved in the control of the phosphorylation level of MYPT1Thr696. Bernadett Kolozsvári et al. Cardiovasc Res 2012;96:494-503 Published on behalf of the European Society of Cardiology. All rights reserved. ? The Author 2012. For permissions please email: journals.permissions@. Effects of CsA on [Ca2+]i and on the phosphorylation of cofilinSer3 and MYPT1Thr696. Bernadett Kolozsvári et al. Cardiovasc Res 2012;96:494-503 Published on behalf of the European Society of Cardiology. All rights reserved. ? The Author 2012. For permissions please email: journals.permissions@. Interaction of MYPT1 with CN as revealed by pull-down assays and colocalization using confocal microscopy. Bernadett Kolozsvári et al. Cardiovasc Res 2012;96:494-503 Published on behalf of the European Society of Cardiology. All rights reserved. ? The Author 2012. For permissions please email: journals.permissions@. Characterization of the interaction between CN and MYPT1 by SPR-based binding assays. Bernadett Kolozsvári et al. Cardiovasc Res 2012;96:494-503 Published on behalf of the European Society of Cardiology. All rights reserved. ? The Author 2012. For permissions please email: journals.permissions@. Effect of CN inhibition by CsA on thrombin-induced phosphorylation of MYPT1Thr696 and MLC20Ser19. Bernadett Kolozsvári et al. Cardiovasc Res 2012;96:494-503 Published on behalf of the European Society of Cardiology. All rights reserved. ? The Author 2012. For permissions please email: journals.permissions@. Influence of CsA on endothelial b