impuritydeterminationandcharacterizationof-nsfinternational.docVIP

Impurity and Contaminant Determination during the GRAS Assessment Process: February 5th, 2016 Meeting Table of Contents 1. Raw Material Impurities/Contaminants 2 1.1 Characterization of the raw material 2 1.2 Contaminant Characterization 2 2. Impurities during the manufacturing process 3 2.1 Manufacturing process Characterization 3 2.2 Impurity and Contaminant Characterization 3 3. Impurity and contaminant evaluation of the GRAS finished product 3 3.1 Single substance 3 3.2 Simple mixture 3 3.3 Complex mixture 3 3.4 Polymer 3 3.5 Substances from botanical of biological sources 3 3.6 Nanomater