华人糖尿病特点及优化降糖治疗.pptVIP

* * * OBJECTIVE—To demonstrate the efficacy, tolerability, and safety of acarbose compared with placebo in patients with type 2 diabetes inadequately controlled with diet and metformin 2,000 or 2,500 mg/day in divided doses . RESEARCH DESIGN AND METHODS—This study had a multicenter randomized double-blind placebo-controlled parallel-group comparison design.The trial lasted 31 weeks and consisted of a l-weed screening period, a 6-weed placebo pretreatment period, and a 24-week period of acarbose or placebo, with a forced titration from 25-50 mg t.i.d. and a titration of 50-100 mg tid that was