按照学校统一安排,定于2013年5月18日 ..pptVIP

Animal rhabdovirus infection cycle 1. Virus binds receptor and enters by endocytosis 2-3. Membrane fusion and core release 4-6. Sequential transcription and translation of mRNAs 7-8. After nucleocapsid protein (N) accumulates, switch from transcription to replication occurs 5,9,10. Glycoprotein (G) enters secretory pathway and is embedded in plasma membrane 11,12. Nucleocapsid with associated phosphoprotein (P) and RdRp (L) are organized into bullet-shaped core particles by matrix protein (M) 13. Cores bud through membrane at sites of G-protein accumulation Rhabdovirus transcription and re