Effect of ulinastatin on paraquat—induced—oxidative stress in human type II alveolar epithelial ce.docVIP

Effect of ulinastatin on paraquat—induced—oxidative stress in human type II alveolar epithelial ce 　　BACKGROUND： Ulinastatin （UTI） is a urinary trypsin inhibitor extracted and purified from urine of males. This study aimed to explore the effects of UTI on paraquat-induced-oxidative stress in human type II alveolar epithelial cells. 　　METHODS： The human type II alveolar epithelial cells， A549 cells， were cultured in vitro. The A549 cells were treated with different concentrations of paraquat （200， 400， 600， 800， 1 000， 1 200 ?mol/L） and ulinastatin（0， 2 000， 4 000， 6 000， 8 000 U/mL） for 24 ho