Alternativesplicin1--2选择性剪切资料.doc

Alternative splicing 选择性剪接 Alternative splicing produces two protein isoforms. 选择性剪接产生两种蛋白亚型。 Alternative splicing is a regulated process during gene expression that results in a single gene coding for multiple proteins. In this process, particular exons of a gene may be included within, or excluded from, the final, processed messenger RNA produced from that gene.[1] Consequently the proteins translated from alternatively spliced mRNAs will contain differences in their amino acid sequence and, often, in their biological functions (see Figure). Notably, alternative splicing allows the human