英文课件-酶4.pptVIP

Enzyme Mechanism: Serine Proteases Active sites of enzymes It is an area of enzyme, It is consist of a few amino acids residues, The residues are closed to each other in space It combines substrate and catalyzes a reaction. Key Terms: Covalent catalysis Acyl-enzyme intermediate Nucleophilic agent Electrophilic agent Preferential binding of transition state complex Catalytic triad Diverse Role of Serine proteases Serine proteases play an important role in many processes, e.g. digestion of dietary protein, blood clotting cascade, and in several pathways of differentiation and developme