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StatementsBased on Survey, Literature and Expert Consensus While there is significant variability in interinstitutional HPV-positive rates in ASC-US Pap tests, monitoring the HPV-positive rate in ASC-US Pap tests is a valuable broad measure of quality. Performance beyond 2 SD’s of the mean should prompt reassessment of diagnostic criteria used in the evaluation of Pap tests and/or investigation of the prevalence of HPV positivity in the population from which the Pap tests are obtained. (Tworek et al, Arch Pathol Lab Med. 2007;131:1525–1531) * ? 2011 College of American Pathologists. All rights reserved. StatementsBased on Survey, Literature and Expert Consensus Monitoring the HPV-positive rate in other diagnostic categories such as LSIL and the comparison of these HR-HPV rates to published benchmarks is also a valuable broad measure of quality for a laboratory and possibly for individuals. * ? 2011 College of American Pathologists. All rights reserved. StatementsBased on Survey, Literature and Expert Consensus When possible, individual ASC-US/HR-HPV results should be compared to ASC-US/SIL ratios for pathologists to determine potential trends in over- and under-diagnosis. * ? 2011 College of American Pathologists. All rights reserved. Consensus Question - Vote 49. If possible, ASC-US/HR-HPV results should be compared to ASC-US/SIL ratios per pathologist as a general quality monitor. A. Yes 58.5% B. No 18.9% C. Unsure 22.6% * ? 2011 College of American Pathologists. All rights reserved. 50. ASC-US reflex HR-HPV results should be monitored to determine potential trends in accuracy of diagnoses: A. Yes 71.9% B. No 18.8% C. Unsure 9.4% * Consensus Question - Vote ? 2011 College of American Pathologists. All rights reserved. 51. HR-HPV DNA results for other diagnostic categories should be monitored to determine potential trends in accuracy of diagnoses. A. Yes 32.3% B. No 50.8% C. Unsure 15.4% D. Other 1.5% Consensus Question - Vote * ? 2011
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