SCIENTIFIC WORKSHOPMENOPAUSAL HORMONETHERAPY.pptVIP

SCIENTIFIC WORKSHOPMENOPAUSAL HORMONETHERAPY*****  Department of Health and Human Services National Institutes of Health Office of the Director October 23-24, 2002 Menopausal Hormone Therapy Historically… Complexities, Confusion But… Hope for Answers From New or Ongoing Research Studies Menopausal Hormone Therapy Average number of NIH funded Grants Contracts FY 1989-1990 11 FY 1999-2000 150 The Women’s Health Initiative Multicenter project examining strategies of prevention control of most common causes of death, disability and impaired quality of life among postmenopausal women. Begun in 1991; recruitment completed in 1998; planned study completion in 2007. 68,000 women in 3 overlapping randomized CT’s and additional 93,676 in parallel OS, to be followed through March 2005 The Women’s Health InitiativeJuly 2002 NHLBI Press Release NHLBI Stops Trial of Estrogen Plus Progestin Due to Increased Breast Cancer Risk, Lack of Overall Benefit Journal of the American Medical AssociationJuly 17, 2002 Risks and Benefits of Estrogen Plus Progestin in Health Postmenopausal Women; Principal Results from the Women’s Health Initiative Randomized Controlled Trial (Writing Group for the Women’s Health Initiative Investigators) The Women’s Health InitiativeJuly 2002 Headlines!!! Citing Risks, U.S. Will Halt Study of Drugs for Hormones Hormone Replacement Study a Shock to the Medical System (N.Y. Times) Goodbye Hormone Replacement Therapy? (abcNEWS.com) Hormone Treatment Is Called Harmful (Washington Post) Doubts on Hormones, Heart Risk Bolstered (Washington Post) The Women’s Health InitiativeJuly 2002 Headlines!!! Hormone Treatment is Called Harmful! Patients Weigh Quitting Drug After Research Indicates Risk NIH Cautions on Hormone Therapy So Much for Hormone ‘Salvation’ The Women’s Health InitiativeEstrogen plus Progestin Results Questions and Passionate Responses and Questions… SCIENTIFIC WORKSHOPMENOPAUSAL HORM