心肌细胞电生理.pptVIP

* Electrical activities of heart Working cell Autorhythmic cell excitability conductivity contractility excitability conductivity contractility automaticity atrium AV node preferential pathway Bundle of His Left and right branch Purkinje fibers Ventricles SA node AV node Bundle of His Purkinje fibers SA node Dominant pacemaker Latent pacemaker ectopic pacemaker 1 Electrical activities of working cells (1) Resting potential (RP) a. most permeable to K+, relatively impermeable to other ions b. [C0][Ci] Inward rectifying K+ channels, Ik1 Na+ pump -90 mV 2K+ 3Na+ Na+ pump Na+-Ca2+ exchanger