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this week in science Size Matters CREDIT: FRED NIJHOUT/DUKE UNIVERSITY Animals regulate their growth so that all organs are mutually proportional, even when growth occurs at different times. However, the mechanism by which this occurs is unknown. Nijhout and Grunert (p. 1693, published online 25 November) performed an analysis of relative wing growth in the tobacco hornworm, Manduca. Animals that were small owing to starvation had smaller wings, due to their slower growth rate, and they also stopped growing earlier than large, well-fed larvae. The insect hormone ecdysone was implicated