Chapter4Hypoxia.pptVIP

Concept Oxgen supply = CaO2× Q Oxygen consumption =（CaO2－CvO2）× Q What kind of hypoxia might occur in septic shock ？ Hypotonic hypoxia PaO2 ＜ 60mmHg → compensation ＜ 30mmHg → severe disturbances Oxygen therapy and oxygen intoxication Oxygen intoxication --- PO2 0.5 atm * Hypoxia Pathophysiology department Tissue cells can’t obtain enough oxygen or can’t fully utilize oxygen metabolic, functional and structural changes CO2－dissolved O2 CO2max O2 saturation（SO2）=