Heavy breathing in the blood bank.pptVIP

Heavy breathing in the blood bank: is it transfusion-related acutelung injury, our anxiety, or both? David F.Stroncek TRALI Although considerable success has been achieved in reducing the risk of transfusiontransmitted infection “transfusion-related acute lung injury” (TRALI) is recognized as the leading cause of transfusion-associated fatalities reported to the FDA TRALI是一種不尋常且較為複雜的輸血反應症狀之一，主要的典型特徵包括：呼吸急促、發燒及低血壓。目前已躍升成為經由輸血所引起的重大傷害之一，甚至導致死亡原因的第二位或第三位，其重要性不容忽視。 直到1980年代後期對症狀及發生原因有更進一步了解之後，才認為是經由輸血所引起的急性呼吸窘迫症候群 定義排除病人本身臨床上所表現的心臟或呼吸系統症狀外，經輸注含血漿的血液製品6小時內，產生急性呼吸困難、肺水腫、血壓降低及體溫升高