急性冠脉综合症患者糖化血红蛋白水平及预后关系.docVIP

急性冠脉综合症患者糖化血红蛋白水平及预后关系 黄问银 （九江学院附属医院心血管内科 江西 九江 332000） 【摘要】 目的：探讨急性冠脉综合征（ACS）患者糖化血红蛋白水平情况及其对ACS 患者预后的影响。方法：102例急性冠脉综合症患者根据根据糖化血红蛋白水平分为糖化血红蛋白正常组(HbA1C6.5%,n=31例)、糖化血红蛋白低危组(6.5%HbA1C 7.5 %, n=36例)、糖化血红蛋白高危组(HbA1C 7.5%,n=35例)三组(分别设为A组、B组及C组)，分别观察各组入院时、3个月后12个月后的极低密度脂蛋白(LDLC)、C反应蛋白(CRP)、体重指数(BMI)、射血分数（EF）及相关心血管不良事件如心绞痛、严重心律失常、再发心肌梗死、肺部感染等并发症发生情况。结果：(1)A组、B组及C组患者入院时LDLC、CRP、BMI及EF值无明显差异( P 0. 05),而3个月后及12个月后C组EF值较入院时未明显改善( P 0. 05)；(2)住院及随访12个月期间C组心血管不良事件心绞痛发生率、肺部感染发生率及死亡率较入院时明显增高( P 0. 05)。且HbA1C与心绞痛、严重心律失常、再发心肌梗死、肺部感染及死亡均呈正相关（r分别为0.412、0.271、0.319、0.251、0.134）。结论：糖化血红蛋白异常不同程度地增加急性冠脉综合症患者心血管不良事件发生率。 【关键词】糖化血红蛋白;急性冠脉综合症;心血管不良事件; The relationship between hemoglobin levels in patients with acute coronary syndrome and prognosis of saccharification Huang aWen Yin Affiliated Hospital of Jiujiang University,Cardiovascular Department of Internal Medicine,Jiangxi Jiujiang 332000 [Abstract] Objective: To investigate the effect of acute coronary syndrome patients with glycated hemoglobin level and its effect on the prognosis of patients with ACS. Methods: 102 cases of patients with acute coronary syndrome according to the levels of glycosylated hemoglobin A1c were divided into normal group (HbA1C6.5%, n=31), glycosylated hemoglobin in low risk group (6.5%HbA1C 7.5%, n=36 cases), glycosylated hemoglobin (HbA1C 7.5% high-risk group, n=35 group (three cases).Low density lipoprotein,C reactive protein (CRP), body mass index (BMI), EF value and related adverse cardiac events such as angina, arrhythmia, myocardial infarction, recurrent pulmonary infection and other complications were observed after admission, after 3、12months. Results: (1) LDLC, CRP, BMI and EF values had no significant difference among group A,B,C after admintion(P 0. 05).The level of EF wasn’t obviously improved after 3 months and 12 months(P 0. 05); (2) The incidence of pulmonary infection incidence rate and mortality of groups C were significantly higher t