Trachea(Generation#1).pptVIP

BBB CSF Plasma CO2 HCO3 + H+ CO2 ?? HCO3 + H+ Respiratory Alkalosis high pHCSF limits Hyperventilation When pHCNS returns to norm (HCO3 pumped out) VE is less restrained Lung Volume Airway Resistance Normal ˉ Recoil Emphysema Fibrosis Normal ?Resistance Obstructive ? Recoil Restrictive time (sec) Volume FRC Inspiration Forced Vital Capacity TLC FEV1.0 FVC 1 sec FEV1.0 = 4 L FVC = 5 L % = 80% RV Normal TLC FEV1.0 FVC 1 sec FEV1.0 = 1.2 L FVC = 3.0 L % = 40% RV Obstructive ?airway resist Restrictive ?lung recoil TLC FEV1.0 FVC 1 sec FEV1.0 = 2.7 L FVC = 3.