自身免疫性肝病治疗进展广西_培训课件.pptVIP

* 3 Conventional and empiric treatments for suboptimal responses to firstline treatment in patients with autoimmune hepatitis. Clinical event Conventional treatments Possible empiric treatments 1st choice 2nd choice 3rd choice 4th choice Treatment failure Prednisone (30 mg daily) and azathioprine (150 mg daily), or prednisone alone (60 mg daily) Prednisone (30 mg daily) plus mercaptopurine (1.5 mg/kg body weight daily) Ciclosporin (5–6 mg/kg body weight daily) or prednisone (30 mg daily) plus mycophenolate mofetil (2 g daily) Tacrolimus (4 mg twice daily) Drug toxicity Azathioprine (2 mg/kg bo