sectionNregulaitionoftranscriptionineukaryoted课程.pptVIP

Section N Regulation of transcription in eukaryotes N1 Eukaryotic Transcription Factors Transcription factor domain structure (link) DNA-binding domains Dimerization domains Transcription activation domains Repressor domains Targets for transcriptional regulation (link) Common features of transcription factors bind specifically to some DNA sites: specific motifs in promoters, upstream regulatory elements (UREs) or enhancer regions. Some factors modulate transcription by protein-protein intracation Activate/repress transcription. N1-2: DNA-bindi