药理学英文题(教研室版).docVIP

Ⅰ.Choice Questions Type A1 .The half-life of a drug is 2 hours, how much is the KA. 0.1 (h-1)B. 0.2 (h-1)C. 0.3 (h-1)D. 0.35 (h-1)E. 2 (h-1)2. Which of the following statements about first-order kinetics elimination is trueA. The elimination rate is fastB. The elimination rate is slowC. There is no relationship between the amount of drug in the bodyand elimination rateD. The elimination of drug is in direct proportion to the bloodconcentration of the drugE. The elimination of drug is in inverse ratio to the amount of drugin the body3. As far as some drug is concerned, which of the following statements concerning the drugs combination with plasma protein is trueA. The higher the binding rate, the stronger the curative effectB. The lower the binding rate, the stronger the curative effectC. The higher the binding rate, the faster the excretionD. There is not relationship between binding rate and curative effectE. All of the above are incorrect4. Which of the following administrations can immediately reach the plateau concentrationA. Decreasing dose, increasing times of administrationB. Decreasing administering intervalC. Increasing administering intervalD. Administration of loading doseE. Frequent administration by iv 5 .In general, the weak acid drugs in basic solution areA. weakly ionized, pass across the biomembrane easilyB. strongly ionized, pass across the biomembrane easilyC. strongly ionized, pass across the biomembrane hardlyD. weakly ionized, pass across the biomembrane hardlyE. all of above are incorrect6. If the stomach juice pH is1. 4 and plasma pH is 7.4, how much is the drug concentration ratio of plasma to stomach juice for a weak acidic drug with pKa 5.4 when the distribution reach to equilibrium？A.50B.100C.1000D.10000E.0.17. All of the following statements are applicable to the sublingual route of administration EXCEPTA. plasma concentration decreased by first pass eliminationB. lipid soluble drugs will be absorbed rapidlyC. Irritant drugs should not