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The Kalman filter based research of T-wave alternans detection algorithm Abstract: As the second largest cause of death in human beings only behind cancer, sudden cardiac death (SCD - Sudden Cardiac Death) is featured as sudden onset and difficult to rescue. Therefore, for these patients, early diagnosis, early intervention is the most effective treatment. TWA (T wave alternans) as the detection of SCD-like illness is an important indicator of how (non-invasive) to obtain accurate data in a TWA research which is focused on in recent years in the industry. This paper presents a modified Kalman filter-based (non-steady state) TWA detection algorithm: First of all, preprocessing, filtering noise and baseline drift of ECG; method using wavelet transform modulus extremum of QRS and T waves, see vehicle features location of the point; further alignment and extracts the T wave T wave matrix; according to the strategy (in accordance with the odd and even) on the T wave matrix re-grouping; Kalman filter were used on two groups of T wave matrix; calculate the difference between two groups of T wave matrix, then the vector modulus maxima to identify the vector through vector maxima modules, and makes the mean vector as the testing standards. Through simulation results,this algorithm for the correlation coefficient of TWA detection values and real values reaches 97%, and not only can it test the rate of T wave alternans, but also can identify short-term T wave alternans. [key word]: TWA Kalman extremum of wavelet transform modulus Sudden Cardiac Death [Introduction]: Sudden cardiac death (SCD-Sudden Cardiac Death) is a death caused by heart attack. According to the agencys statistics, sudden cardiac death has become the second largest cause of death after cancer. There are about 45.000 cases in United States, and over 1.8 million cases per year in China Additionally, the increasingly serious environmental pollution, the pressure continued to increase, this figure is con

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