MAPK在葡萄糖及AngⅡ致血管平滑肌细胞增殖反应中的作用.docVIP

MAPK在葡萄糖及AngⅡ致血管平滑肌细胞增殖反应中的作用 作者：张严高，秦永文，吴弘，王文清，文军慧，李闻捷 【关键词】 丝裂原活化蛋白激酶；细胞外信号调节MAP激酶类；血管紧张素Ⅱ；高糖；肌,平滑,血管/细胞学；增殖反应 Regulation of MAPK in glucose/angiotensin Ⅱinduced proliferation of vascular smooth muscle cells 【Abstract】 AIM: To study the role of mitogen activated protein kinase in glucose/angiotensin Ⅱinduced proliferation of rat vascular smooth muscle cell . METHODS: The protein sythesis rate and protein content were used as the indexes of VSMC proliferation in our DNA synthesis rate was quantified by ［3H］thymidine incorporatio