课件3,12.pptVIP

生活史（Cycle parasitaire） 生活史（Cycle parasitaire ） Pathogenisis: 3 stages ： 1. Invasion – 1 week, first symptoms appear 12 hours to 2 days following ingestion of trichina cysts. 2. migration of larvae – 2 week to 2 months, penetration and encystment in skeletal muscles 3. calcification (if one survives stage2!) - occurs several months after infection - calcium is deposited around the cysts - Larva eventually die in a year or longer Diagnosis: Muscle biopsy Treatment : Mebendazole, Albendazole Prevention Thorough cooking (temperature above 58o C) 2. freezing for 20 days will kill temper