7286例儿童血清肺炎支原体抗体检测结果分析.docVIP

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7286例儿童血清肺炎支原体抗体检测结果分析.doc

7286例儿童血清肺炎支原体抗体检测结果分析   摘要:目的:了解某市儿童肺炎支原体的感染情况,检测血清肺炎支原体抗体的阳性率。方法:采用酶联免疫吸附法(ELISA法)对我院收治的7286例急性呼吸道感染患儿的血清进行肺炎支原体特异性抗体(IgM)检测。结果:本组患儿的肺炎支原体IgM抗体阳性率为40.58%(2957/7286);1岁的患儿肺炎支原体IgM抗体阳性率为30.66%,明显低于其他年龄组(P0.01);冬季患儿的肺炎支原体IgM抗体阳性率明显高于其他季节(P0.05)。结论:肺炎支原体感染已成为某市儿童急性呼吸道感染的主要病原体之一,加强对患儿进行肺炎支原体抗体检测,可为临床诊断和治疗提供依据。   关键词:儿童 急性呼吸道感染 肺炎支原体Analysis of 7286 cases of children serum Mycoplasma pneumoniae antibody test results   Gao Shihua   Abstract:Objective:To study the infection status of Mycoplasma pneumonia among the children in ×× city, and detect the positive rates of Mycoplasma pneumonia antibodies in serum. Methods:Enzyme linked immunosorbent assay ( ELISA) was used to detect Mycoplasma pneumonia antibodies in serum of 7286 children with acute respiratory infection.Result:The mycoplasma pneumonia IgM antibody positive rate of the children was 40.58% (2957/7286). The mycoplasma pneumoniae IgM antibody positive rate under 1 years old was 30.66%, which significantly lower than other age groups (P0.01). The mycoplasma pneumoniae IgM antibody positive rate of children in Winter obviously was higher than other seasons (P0.05). Conclusion:Mycoplasma pneumonia infection is one of the major pathogens of acute respiratory infection among the children in ×× city. It is useful for clinical diagnosis and treatment to detect Mycoplasma pneumonia antibodies in children with acute respiratory infection.   Keywords:Children Mycoplasma pneumonia Acute respiratory infection   【中图分类号】R-1 【文献标识码】B 【文章编号】1008-1879(2012)12-0472-02   肺炎支原体(Mycoplasma pneumonia)是儿童呼吸道感染的重要病原体之一,其感染除能引起呼吸道感染(咽炎、支气管炎、肺炎)外,还可通过血行播散或免疫机制引起心肌炎、肾炎、脑膜炎、肝炎、溶血性贫血、关节炎、血小板减少性紫癜等肺外并发症[1-3]。近年来,肺炎支原体感染的发病率逐年上升[1]。由于肺炎支原体感染的临床表现缺乏特异性,根据临床症状很难与其它病原微生物感染进行鉴别,因此,实验室诊断尤为重要。为了解某市儿童肺炎支原体的感染情况,本组采用酶联免疫吸附法(ELISA法)对我院收治的7286例急性呼吸道感染患儿的血清进行肺炎支原体IgM抗体检测,现报告如下。   1 资料与方法   1.1 一般资料。2007年1月~2012年6月在我院收治的急性呼吸道感染患儿7286例,其中男4036例,女3250例;1岁的患儿3050例,1~3岁2257例,3~6岁1183例,≥6岁796例;病程3~15d;全部患者均行胸部X线片检查,符合《诸福棠实用儿科学》的诊断标准[4]。   1.2 方法。

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