抗生素的合理应用- 张伦理_图文.pptVIP

* * 抗菌药物在孕妇的应用 妊娠期可选用的药物 包括青霉素类、头孢菌素类、其他?-内酰胺类、林可和克林霉素、磷霉素等。 只有相对安全，尚无绝对安全的药物。 * * 谢 谢 Thank You * * This slide represents key factors involved in antimicrobial therapy. Once the dose is administered, pharmacokinetic parameters then describe what happens to the drug once it enters the body. Absorption from the GI tract is essential for oral therapy. Once in the blood stream critical factors for success include distribution of the drug into the infected tissues. How long a drug remains in the blood stream is determined by half-life (metabolism or excretion) The