消旋卡多曲颗粒联合儿泻停颗粒治疗轮状病毒肠炎的效果.docVIP

消旋卡多曲颗粒联合儿泻停颗粒治疗轮状病毒肠炎的效果 　　[摘要] 目的 探讨消旋卡多曲颗粒联合儿泻停颗粒治疗小儿轮状病毒肠炎的效果。 方法 选择2010年12月～2012年12月浙江省诸暨市中心医院儿科门诊确诊为小儿轮状病毒肠炎102例，将其随机分为治疗组和对照组，各51例。对照组给予蒙脱石散剂，1岁以下每日1袋，1～2岁每日1～2袋，2岁以上每日2～3袋，均分3次服用，疗程为3 d；治疗组给予消旋卡多曲颗粒口服1.5 mg/（kg?次），3次/d，疗程为3 d；儿泻停颗粒，6个月，1 g/次；6个月～2岁，2 g/次，2次/d，疗程为3 d。 结果 治疗组显效29例，有效15例，无效7例，有效率为86.3%；对照组显效12例，有效17例，无效22例，有效率为56.9%，两组有效率比较差异有高度统计学意义（P 0.01）；治疗组退热时间为（2.62±1.49）d，止泻时间为（3.13±1.83）d，止吐时间为（3.16±0.83）d，脱水纠正时间为（2.15±0.53）d；对照组退热时间为（4.86±1.57）d，止泻时间为（6.79±2.44）d，止吐时间为（4.53±0.87）d，脱水纠正时间为（3.36±0.84）d，两组比较，差异均有高度统计学意义（均P 0.01）。 结论 消旋卡多曲颗粒联合儿泻停颗粒治疗小儿轮状病毒肠炎效果确切，值得推广应用。 　　[关键词] 消旋卡多曲颗粒；儿泻停颗粒；轮状病毒肠炎；疗效 　　[中图分类号] R725.6；R512.5[文献标识码] A[文章编号] 1673-7210（2014）06（a）-0077-04 　　 　　Efficacy of Racecadotril Granules combined with Erxieting Granules in treatment of infant with rotavirus enteritis 　　YU Qing1 PENG Cangjiao2 GUAN Minchang3 XU Zhongliang4 　　1.Department of Pediatrics, Zhuji Central Hospital, Zhejiang Province, Zhuji 311800, China; 2.Taizhou Hospital of Taizhou Enze Medical Center, Zhejiang Province, Linhai 317000, China; 3.Luqiao Hospital of Taizhou Enze Medical Center, Zhejiang Province, Taizhou 318050, China; 4.Quzhou Hospital of Traditional Chinese Medicine, Zhejiang Province, Quzhou 324000, China 　　[Abstract] Objective To observe the effect of Racecadotril Granules combined with Erxieting Granules in the treatment of infantile rotavirus enteritis. Methods 102 children out-patients with infantile rotavirus enteritis in Department of Pediatrics of Zhuji Central Hospital from December 2010 to December 2012, according to their consulting order, whom were randomly divided into control group (n=51) and the observation group (n=51). Patients in control group were taken montmorillonite, less than 1 year of age, 1 bag a day , 1 to 2 years , 1 to 2 bags a day, more than 2 years of age, 2 to 3 bags a day, three times a day on 3 successive days. The patients in observation group were taken Racecadotril Granules 1.5 mg/kg per time, three times a day