慢性获得性脱髓鞘性多发性神经病17.docVIP

Chronic acquired demyelinating multiple neuropathy 1. Curr Neurol Neurosci Rep. 2014 Oct;14(10):487. doi: 10.1007/s11910-014-0487-z. Neurologic manifestations of gastrointestinal and liver diseases. Ferro JM(1), Oliveira S. Author information: (1)Department of Neurosciences, Service of Neurology, Hospital de Santa Maria, University of Lisbon, Av. Prof. Egas Moniz, 1649-035, Lisboa, Portugal, jmferro@fm.ul.pt. Hepatic and gastrointestinal disorders can produce a wide spectrum of neurologic complications both affecting the central nervous system (CNS) and the peripheral nervous system. These manifestations range in severity from coma in acute liver failure and acute pancreatitis, to minor cognitive changes in chronic portosystemic encephalopathy and hepatitis C. Cerebrovascular diseases can complicate hepatitis C infection and inflammatory bowel disease. Demyelinating disorders may co-exist with inflammatory bowel disease. Anti-tumor necrosis factor alpha drugs may induce demyelination. Ataxia may occur in malabsorption syndromes and in gluten related disorders. Characteristic movement disorders are key features of acquired hepatocerebral degeneration and of Whipple disease. Multiple types of neuropathy can be found in association with hepatitis, inflammatory bowel disease and gluten related disorders. PMID: [PubMed - indexed for MEDLINE] 2. Neuroimaging Clin N Am. 2013 May;23(2):321-36. doi: 10.1016/j.nic.2012.12.010. Epub 2013 Jan 23. Mimics and rare presentations of pediatric demyelination. OMahony J(1), Shroff M, Banwell B. Author information: (1)Divison of Neurology, Department of Pediatrics, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada. This article reviews the features that should prompt consideration of diseases that mimic acquired demyelinating syndromes and multiple sclerosis using vignettes to highlight unusual clinical and radiologic features. Cases of transverse myelitis, spinal infarctio