ppt课件-葡萄球菌（ staphylococcus）.pptVIP

Cell Wall Location Ubiquitous Normal flora Skin Mouth Nose Throat Predisposing factors Immunosuppression Concurrent disease AB resistance Enzymes Coagulase Catalase Hyaluronidase Lipase Beta lactamase Staphylokinase (plasminogen activator) Proteases DNase FAME (fatty acid modifying enzyme) Staphylococcus Toxins Cytolytic Toxins Alpha = β hemolysis Beta = sphingomyelinase Delta Gamma Leukocidin = hemolysis Leukotoxin = WBC destruction Exfoliative toxin ETA and ETB Protease esterase activity Toxic Shock toxins Enterotoxins (A-E) Virulence Factors Summary Staphylococcal disease summary VRSA Op