Micro RNA在心肌梗死中课件.pptVIP

microRNA in Acute Myocardial Infarction 河北医科大学第三医院急诊科 董士民 dsm_123@163.com mirRNA are endogenous, noncoding,single-stranded RNAs of ~22 nucleotides and constitue a novel class of gene regulators Currently, about 600 mirRNAs have been cloned and seguenced in humans ,and the estimated number of mirRNA genes is as high as 1,000 in the human genoume Functionally, an individual miRNA is as important as a transcription factor because it is able to regulate the expression of its multiple target genes As a group,mirRNAs are estimate to regulate over 30% of the genes in a cell It