人体生物化学与疾病讲诉.ppt

* In contrast, the developing world currently has a relatively young population that is rapidly increasing. The number of elderly people in developing countries will increase more dramatically over the next few decades as the population ages. As a consequence, the number of people with dementia will also rise. Support continued . . . According to Kunst over-expression of normal SOD1 accelerates disease onset and progression However, a decrease or increase in SOD1 activity is not sufficient to cause ALS in mice From PubMed Hypothesis #2 SOD1 may lose its ability to bind zinc (Zn), Copper (Cu)