微生态制剂及在儿童的应用分析.ppt

* * * * Optional Speaker Notes: Environmental changes in the industrialized world, as well as changes of life style in western societies, and medicine, have reduced the extent of microbial contact at an early age. These changes affect the initial establishment of the microflora. The hygiene hypothesis, first proposed by Strachan in 1989, offered, in part, an explanation to the increasing prevalence of atopic conditions. The idea was based on epidemiological observations, suggesting an inverse correlation between family size and the prevalence of allergic rhinitis. Today, an extended