三维彩色血管能量成像诊断乳腺肿瘤的应用价值.docVIP

三维彩色血管能量成像诊断乳腺肿瘤的应用价值 nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; nbsp;作者：殷平　李文巨　李波　蒋晶 【摘要】nbsp; 　　［目的］ 探讨三维彩色多普勒能量图 (3D-CPA) 在乳腺良恶性肿瘤鉴别诊断中作用。［方法］ 对87例102个乳腺肿块进行3D-CPA检查，其中乳腺癌35个，良性肿瘤67个，并对肿瘤血管三维图像进行半定量分析，比较乳腺良性肿瘤组及恶性肿瘤组的血流分级和血管形态差异。［结果］ 乳腺良恶性肿瘤的血流分级和血管形态不同。乳腺良性肿块以Ⅰ级血流为主，而乳腺癌则以Ⅲ级血流为主 (Plt;0.01)。乳腺癌以不规则型和穿入型血流乳腺癌组为主，而良性肿瘤则大部分显示为环绕型和抱球型 (Plt;0.01)。以穿入型和不规则型诊断乳腺癌，其敏感性为96.29％，特异性为84.61％。［结论］ 3D-CPA可作为乳腺良恶性肿瘤的鉴别诊断新的补充手段。 【关键词】nbsp; 超声检查　三维彩色血管能量显像　乳腺肿瘤　血管模式 　　Abstract: ［Purpose］ To evaluate the role of three-dimensional color power angiography (3D-CPA) in the differential diagnosis of breast tumor. ［Methods］ Eighty-seven cases with 102 breast tumors (35 malignancies and 67 benign tumors) were assessed with 3D-CPA. Half-quantitative analysis of tumor vascularity was performed according to 3D-tumor vascular patterns. Blood flow grade and vascular patterns were compared between benign and malignant groups.［Results］ There were different three-dimensional tumor vessel patterns and blood flow grade between malignant and benign groups. GradeⅠ blood flow was mainly seen in benign group, while grade Ⅲ was predominantly demonstrated in malignant group (Plt;0.01). Encircled vascular patterns and basket vascular patterns were the characterization of benign breast tumor, however, irregular and penetrating vascular patterns were the characterization of malignant tumor (Plt;0.01). The sensitivity and specificity in diagnosis for breast cancer according to the irregular and penetrating vascular pattern were 96.29% and 84.61%, respectively. ［Conclusion］ 3D-CPA can be used as a supplementary modality in the differential diagnosis for breast tumor. nbsp;nbsp;nbsp; Key words: ultrsonography; three-dimensional color power angiography; breast neoplasm; vascular pattern nbsp;nbsp;nbsp; 肿瘤血管生成在肿瘤生长和转移中起重要作用，彩色多普勒血流成像(CDFI)是目前诊断乳腺肿瘤的重要手段。本文对87例102个乳腺肿块在彩色多普勒显像的基础上行三维彩色血管能量成像技术（three-dimensional color power angiography,3D-CPA）, 前瞻性研究肿块血流分布情况并对肿块内血流半定量分析，