缩宫素与卡前列甲脂栓联合预防产后出血患者的临床治疗.docVIP

缩宫素与卡前列甲脂栓联合预防产后出血患者的临床治疗 　　【摘要】目的：观察缩宫素与卡前列甲酯栓联合预防产后出血的临床疗效。方法：将我院正常分娩的240例非高危产妇作为研究对象，按照随机数字表法将其分为观察组和对照组，对观察组采用缩宫素与卡前列甲酯栓联合预防产后出血，每组120例，分析比较两组治疗患者的临床效果。结果：两组在胎儿娩出至放药前出血量差异无统计学意义（P0.05），产后2h出血量及产后24h累计出血量的比较发现，观察组明显低于对照组，差异有统计学意义（P0.05）；观察组用药后不良反应的发生率5.0%明显低于对照组的12.5%，差异具有统计学意义（P0.05）。结论： 缩宫素联合卡前列甲酯栓能有效减少产后出血量和出血发生率，用药方便安全，具有较高的临床应用价值。 　　【关键词】缩宫素；卡前列甲酯栓；产后出血 　　Abstract：Objective： To observe the clinical curative effect of Oxytocin combined with Carboprost on preventing postpartum hemorrhage. Methods： 240 cases of pregnant women with normal parturition other than high risk pregnant were selected to be divided into control group and observation group， each group with 120 cases. The control group received Oxytocin to prevent postpartum hemorrhage， while the observation group received Oxytocin combined with Carboprost. Then compared the clinical effect of the two groups.Results： The difference about the amount of foetuses bled during the time between delivery and receiving drug treatment was of no statistically significant（P0.05）. The amount of bleeding of the observation group was significantly lower than the control group（P0.05）.The rate of adverse events after drug treatment in the observation group was 5 percent， which was lower than the control group significantly （P0.05）， whose rate was 12.5 percent. Conclusion： Oxytocin combined with Carboprost can reduce the amount of bleeding and the rate of postpartum hemorrhage， which is convenient to use and has the clinical application value. 　　【中图分类号】R4 【文献标识码】B 【文章编号】1671-8801（2015）03-0071-02 　　统计资料表明，产后出血作为产科常见而严重的并发症危及着产妇生命安全，位于产妇六大死因之首，子宫收乏力是产后出血的主要原因，占产妇产后出血原因总数的90%。为了降低产妇死亡的几率，必须在分娩过程中积极促进子宫收缩，预防产后出血[1]。为探讨简单、安全、有效的方法，寻求安全有效的临床技术预防产妇产后出血，本文对缩宫素联合卡前列甲酯栓预防产妇产后出血的临床治疗进行了观察研究，现报告如下。 　　1 资料与方法 　　1.1临床资料 　　选择2014年4月―2015年4月在我院住院的240例产妇作为研究对象。按照随机数字表法将其分为观察组和对照组，每组各120例。观察组孕妇年龄21-31岁，平均年龄（26.4±3.5）岁，体重78-101kg，平均（85.7±4.2）kg；对照组孕妇年龄20.5-33岁，平均年龄（25.3±4.1）岁，体重76-102kg，平均（85±5）kg。两组孕妇均为足月正常妊娠、阴道分娩、单胎头位、无妊娠并发症及合