ppt课件-thegrierconsentdecree-foodanddrugadministration.pptVIP

Using Automated Databases to Assess Fetal Effects of Maternal Medication Use William Cooper, M.D., M.P.H. Vanderbilt University School of Medicine Objectives Discuss role of automated databases in conducting studies of maternal drug exposures and fetal effects Review findings from OWH funded studies Consider future directions Lessons Learned from Thalidomide Epidemiology played a critical role Response to signal Epidemiologic assessment Placenta not protective Need for regulation and monitoring of medications and effects on fetus Population-Based Studies Provide estimates of potential expos