综合营养干预对妊娠期糖尿病产妇糖脂代谢水平影响的临床研究.docVIP

综合营养干预对妊娠期糖尿病产妇糖脂代谢水平影响的临床研究 　　[摘要] 目的 分析妊娠期综合营养干预对妊娠期糖尿病产妇糖脂代谢水平的影响。 方法 选择在本院接受治疗的妊娠期糖尿病产妇作为研究对象，随机分为接受常规干预的对照组及接受妊娠期综合营养干预的观察组，比较其干预后的血糖水平、血脂水平、母婴围生结局等差异。 结果 观察组孕妇接受干预后的空腹、餐后及零点血糖水平均明显低于对照组孕妇（P0.05）。观察组孕妇接受干预后的甘油三酯、胆固醇、低密度脂蛋白（LDL）和载脂蛋白B（ApoB）水平明显低于对照组，高密度脂蛋白（HDL）和载脂蛋白A-Ⅰ（ApoA-Ⅰ）水平明显高于对照组（P0.05）。观察组孕妇接受干预后的各项母婴围生期并发症发生率均显著低于对照组孕妇（P0.05）。 结论 妊娠期综合营养干预可以明显降低糖尿病孕妇的血糖及血脂水平，降低围生期母婴并发症的发生率，保障母婴生命安全。 　　[关键词] 妊娠期糖尿病；综合营养干预；围生期结局 　　[中图分类号] R473.71 [文献标识码] B [文章编号] 2095-0616（2015）14-69-03 　　Effect of comprehensive nutrition intervention on gestational diabetes womens glucose and lipid metabolism 　　CHEN Liping 　　Zhongcun Hospital in Panyu District of Guangzhou City， Guangzhou 511495， China 　　[Abstract] Objective To analyze the effect of comprehensive nutrition intervention on gestational diabetes womens glucose and lipid metabolism. Methods Choosed gestational diabetes women in our hospital as study object， randomly divided into control group receiving conventional intervention and observation group receiving comprehensive nutritional interventions， compare their blood glucose levels， blood lipid levels， maternal and child perinatal outcomes. Results observation group womens blood glucose levels were significantly lower than control group women（P0.05）. Observation group womens TG、TC、LDL、ApoB levels were significantly lower than control group， HDL and ApoA-Ⅰlevels were significantly higher than control group（P0.05）. Observation group womens maternal perinatal complications were significantly lower than control group women （P0.05）. Conclusion Comprehensive nutritional intervention during pregnancy can significantly lower blood glucose and lipid levels in diabetic pregnant women， reduce the incidence of perinatal maternal complications ， ensure the safety of mother and child. 　　[Key words] Gestational diabetes； Comprehensive nutrition intervention； Perinatal outcomes 　　妊娠期糖尿病（GEM）目前在临床孕妇中的发病率越来越高，这与人们对于孕期的饮食观念错误关系密切[1]。GEM可造成患者孕期血糖剧烈波动，若不及时干预可造成母婴健康受损，包括妊娠期高血压、羊水过多、