Chapter49AntineoplasticDrugs.pptVIP

Chapter 49 Antineoplastic Drugs Department of pharmacology Liu xiaokang(刘小康） 2010,3 Categories: 1) Antimetabolites: a) Folic Acid Analogs (Methotrexate, MTX). b) Pyrimidine analogs (Fluorouracil, 5-FU; Fluorodeoxyuridine; Cytarabine). d) Purine analogs (6-Mercaptopurine, 6-MP; 6-Thioguanine, 6-TG). 2) Alkylating agents: Nitrogen mustards; Cyclophosphamide; Thiotepa. 3) Natural products: Vinca alkaloids (Vincristine; Vinblastine; Vinorelbine); Paclitaxel (Taxol? ) 4) Antiumor antibiotics: Anthracyclines (Doxorubicin hydrochloride, Daunorubicin, Bleomycin) 5) Miscellaneous agents: Cisplat