年代学2013-6a要点.ppt

* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * The analyte may be ionized thermally, by electric fields or by impacting energetic electrons, ions or photons The ions can be single ionized atoms, clusters, molecules or their fragments or associates Ion separation is effected by static or dynamic electric or magnetic fields Kienitz H. (1968) Einführung in Massenspektrometrie, Kienitz H., editor, Verlag Chemie: Weinheim 带能量的中性原子或大离子团也可以使分析物质或粒子产生离子化作用 在无场环境下，相同动能的离子或带电分子也可以按照不同m/z比值进行分离，如飞行时间质谱方法 早期质谱研究和仪器设计以磁式、静态分析为主，由无聚焦、单聚焦向双聚焦发展，主要以非商售、研究单位或研究者自行设计为主 上世纪中叶，出现以非磁式、动态分析的质谱仪器，出现分析仪器联用，仍然以自行设计为主 上世纪中后期，大量的商售质谱仪器出现，针对分辩率、灵敏度、精度以及分析方法进行大量的研制；激光和二次离子源的出现，促进固体物质微区/原位分析的发展；加速器质谱技术的出现 二十世纪末以来，多种高精度、高灵敏度、高分辩率的大型质谱仪器先后问世，由于理论、技术和计算机等的高速发展，无论离子源、质量分析器、检测器的制造技术，还是分析方法、数据处理和仪器操作上均获得质的飞跃 A long history in Thermal Ionisation Mass Spectrometry (TIMS) since 1973 MM30- single collector. VG54E- single/double collector VG354- 5collector VG Sector- up to 9 collectors VG Sector 54- 9 collectors + ESA MM Sector 54- 9 collectors + WARP MM IsoProbe-T-9 collectors + 7ion counters IsoProbe-T TIMS A product of the GV company (MicroMass) Features of the IsoProbe-T Wide Magnet and Flight Tube: This permits the instrument to measure an 18 % mass window at the collector. This will allow simultaneous measurement of the 6Li+ isotope and the 7Li+ isotope. Use of M 17 Multicollector Block: Up to 17 collectors can be accommodated in this block with the possibility of including Multiple Ion Counters for the measurement of very small ion beams in the static mode. Features of the IsoProbe-T Fully automated positioning of Collectors: A new multiple motor controller has been developed which provides feed-back of the collector position. New Windows NT based Software Suite: The MassLynx software suite used throughout the Micromass product range has been extended to the Isotope ratio products. A completely new working interface, IsoLynx, has been developed which permits the direct use