沈阳地区1228例干眼症的临床观察分析.doc

沈阳地区1228例干眼症的临床观察分析 摘 要 目的：探讨干眼症患者的发病特点及临床特征。收集200年月至20年月就诊于的例干眼症患者的资料进行干眼症问卷调查和检查包括裂隙灯检查、角膜荧光素染色、泪膜破裂时间(breakup time,BUT)检查和基础泪液分泌试验(Schirmertest,SIt),并对临床资料进行分析。结果在12例患者中,干涩感(%)、异物感(%)、眼疲劳(%)、畏光/流泪（47.9%）、眼痒（40.9%）烧灼感（32.3%）、视物模糊/视力下降%）为干眼症最常见的症状。干眼症患者的临床症状具有多样性特点,尤以眼干涩、视疲劳、眼痒和视物模糊/视力下降最为多见Clinical characteristics of 1228 patients with dry eye syndrome in Shenyang Abstract Purpose: To analysis the main clinical manifestation of dry eye in Shen yang. Methods: Collect 1228 dry eye patients from 2008.09 to 2010.05 who examined at He Eye Hospital in Shen yang. Patients with dry eye were investigated by questionnaire and clinical examination which include slit-lamp examination, corneal fluorescent stain test,tear break-up time(BUT) and Schirmer I tear test were taken and make analysis on their clinical data. Results: Among them, women were 755 person while men were 437 person. In which, dry sense(89.0%)，foreign body sensation(83.9%)，eye fatigue(67.8%)，photophobia or tearing(47.9%)，itching(40.9%)，cauterization(32.3%) and blurred vision(28.2%) are the most common symptoms. Menopause，sit up or insomnia，long-term use of computer，smoking,taking hypotensive drugs and heart rate control drugs are the most common reason which can induce dry eye. Conclusion: The clinical characteristic of dry eye is vatiable, especially dry sense， foreign body sensation，eye fatigue，photophobia or tearing，itching(40.9%)，cauterization and blurred vision are the most common symptoms. Menopause，sit up or insomnia，long-term use of computer，smoking，taking hypotensive drugs and heart rate control drugs are the most common reason which can induce dry eye. Key Words:dry eye reason clinical characteristic analysis 沈阳地区1228例干眼症的临床观察分析 前 言 2007年国际干眼病专题研究会(DEWS)[1]将1995年美国国立眼科研究所提供的干眼定义[2]进行了补充,重新定义为:干眼是一种能引起眼部不适、视觉障碍和泪膜不稳定,伴有泪膜渗透压增高和眼表炎症的泪液及眼球表面多因素疾病。干眼症的主要症状为眼干眼痒异物感、烧灼感、畏光、视疲劳及视物模糊。近年来干眼的数量不断增多，年龄分布范围也逐渐拓宽,为我国干眼研究提供一定的线索，本研究对1228例眼科门诊患者进行问卷调查及干眼相关检查，现报道如下。 对 象 和 方 法 1. 对象