ppt课件-bacterial damageto host cells- universityof southern（细菌damageto宿主细胞-南大学）.pptVIP

* * * * * Establishment of Infection In order to cause disease pathogen must follow a series of steps Gain entrance to host Adherence Colonization Avoid Host Defenses Cause host damage Portals of entry 1. Mucus membranes Respiratory tract Gastrointestinal tract Genitourinary tract Placenta 2. Skin 3. Parenteral route Bite, puncture, injection, wound Most microbes have a preferred portal of entry Streptococci when inhaled may cause pneumonia; when ingested they do not A few microbes cause illness no matter how they enter May cause different illness based on portal Plague has 2 forms