ppt课件-data integration, gene ontology,andthe mouse（数据集成、基因本体和老鼠）.pptVIP

Data Integration, Gene Ontology, and the Mouse* Joel Richardson, Ph.D. Mouse Genome Informatics Group The Jackson Laboratory Bar Harbor, Maine 04609 We have the human sequence: OK, now what? One species is not enough: model organisms (one strain is not enough) comparative studies The sequence is just the beginning sequence variants gene regulation and interaction networks non-coding functional elements environmental effects Genotype to phenotype The Mouse the premier animal model for studying human disease 95% same genes same diseases, similar reasons (e.g., cancer, hypertension, diabetes, os