端粒酶逆转录酶反义寡核苷酸对甲状腺癌细胞凋亡的影响.docVIP

端粒酶逆转录酶反义寡核苷酸对甲状腺癌细胞凋亡的影响 作者：石梅，易军,凌瑞，宫卫东，付莉 【关键词】 甲状腺肿瘤；,寡核苷酸类,,反义；,端粒酶逆转录酶 　　Effect of antisense oligonucleotides encoding telomerase reverse transcriptase on thyroid carcinoma cell apoptosis 　　【Abstract】 AIM: To investigate the effect of antisense oligonucleotides (ASODN) encoding telomerase reverse transcriptase (TERT) mRNA on thyroid carcinoma (TC) cell apoptosis. METHODS: The ASODN and sense oligonucleotides (SODN) encoding TERT were delivered respectively to the TC cells in vitro. The effect of ASODN encoding TERT mRNA on TC cell apoptosis